I have some difficulties to solve this easy problem, could someone help me?
Is $4^{1000}-6^{500}$ divisible by $10$?
I have some difficulties to solve this easy problem, could someone help me?
Is $4^{1000}-6^{500}$ divisible by $10$?
Your expression can be written as $16^{500}-6^{500}$. Recall that $a^n-b^n$ is divisible by $a-b$ for $n \in \mathbb{N}$.
HINT: What is the right-most digit of $4^{1000}$? What is the right-most digit of $6^{500}$? What does that tell you about the right-most digit of $4^{1000}-6^{500}$?
We can see that $4^1 = 4$, $4^2 = 16$, $4^3 = 64$, etc. It starts out with 4 as the last digit, which when multiplied by 4 gives you a 6, which when multiplied by a 4 gives you a 4, setting up the pattern of 6 as the last digit for even powers. Therefore $4^{1000}$ has 6 as its last digit. Clearly all powers of 6 have 6 as their last digit because if you multiply something that ends with 6 by 6 the product will end with a 6 since $6\times6=36$. Since the last digits are both 6, when you subtract you get 0 as the last digit, which means the difference is divisible by both 5 and 2 and is therefore divisible by 10.
It is unclear from your question whether you require a general method. I've upvoted three of the other four answers here since they are all good. In particular the current best is the slickest trick and the next two are good generalizations.
That said, as I mentioned in the comments, the obvious approach should not be overlooked for a needlessly clever one. If you don't care about generality, then you can just evaluate the expression:
114813069527425452423283320117768198402231770208869520047764273682576626139237031385665948631650626991844596463898746277344711896086305533142593135616665318539129989145312280000688779148240044871428926990063486244662594025981424571409593728603035337632150388437182293551503447920102344948592677163033795451303978737969476432059651388725310756060866840299888538186292656743914465551536060049704715010157731117606858818025434780563119782817848700370999189150586174225945806076652256660690364965642083240783804920125367468611373661642590443113055089150622765944210552490560361847080855944387010578350080000
From here, it's pretty clear that it is divisible by $10$. I hesitate to post this as an answer, since it's by far the dumbest--but I think it's important to remember that elegant solutions aren't always needed to solve simple problems. Simple problems sometimes just have simple answers.