Is there a typo in the question?
1. If YES and if the equation of the circle should read $x^2+y^2=5^2$, then the solution is much simpler, and would be as follows:
Circle has centre $O(0,0)$ and radius $5$.
Point $P(-4,3)$ lies on the circle.
Gradient of $OP$ is $m=-\frac34$.
Tangent to circle at $P$ is perpendicular to OP, and has gradient $m'=-\frac1m=\frac43$.
Hence equation of tangent is:
$$\begin{align}y-3&=m'(x-(-4))\\
y-3&=\frac43(x+4)\\
y&=\frac43x+\frac{25}3\qquad \blacksquare \end{align}$$
2. If NO, then the solution is more messy, and it is then assumed that the question is meant to read the "tangents to the circle which passes through the point $(-4,3)$" rather than "tangents to the circle and the point".
Equation of line passing through $P(-4,3)$ with gradient $m$ is
$$y-3=m(x+4)\\
y=mx+(4m+3)$$
At intersection with circle,
$$x^2+(mx+(4m+3))^2=5\\
(1+m^2)x^2+2m(4m+3)x+(4m+3)^2-5=0\\$$
For tangency,
$$\begin{align}
[2m(4m+3)]^2&=4(1+m^2)[(4m+3)^2-5]\\
(4m+3)^2-5(1+m^2)&=0\\
11m^2+24m+4&=0\\
(m+2)(11m+2)&=0\\
m&=-2,-\frac2{11}
\end{align}$$
Hence equations of tangents are:
$$y=-2x-5$$
and
$$y=-\frac2{11}x+\frac{25}{11}$$