I am wondering if the following is true:
Let $U, V \subset \mathbb{R}^n$ be open sets. Suppose $\pi_i(U) =\pi_i(V) = {1}$ for all $i = 0,1,2,3, ...$ Then $U$ and $V$ are homeomorphic.
I came about this question after reading Hatcher's proof that the "house with two rooms" is contractible.