Let $k$ and $m$ be positive integers with $k>m$. Then the partial sums of $$ 1-\binom{k}{1} + \binom{k}{2} - \cdots (-1)^m\binom{k}{m} $$ has alternating signs.
(The partial sums of the given sum are $P_1=1$, $P_2=1-\binom{k}{1}$, $P_3=1-\binom{k}{1}+\binom{k}{2}$, etc)
I arrived at the above problem while trying to show the follwoing (known as Bonferroni inequalities):
Let $A_1, \ldots, A_n$ be events of a probability space. For a subset $I$ of $\{1,\ldots, n\}$, write $A_I$ to denote $\bigcap_{j\in I}A_j$. Further, denote $\sum_{|I|=i}P(A_I)$ as $\sigma_i$. We agree by convention that $\sigma_0=1$.
Then the partial sums of $$ P(A_1^c\cap A_2^c\cap \cdots\cap A_n^c)-\sigma_0+\sigma_1-\sigma_2\cdots $$ have alternating signs.