The 8 factor pairs of e.g. 462 are
$((1, 462), (2, 231), (3, 154), (6, 77), (7, 66), (11, 42), (14, 33), (21, 22))$.
Of the 16 non-negative integers which are the sums and differences of these pairs (such as $462+1=463$, $462-1=461$, $21+22=43$, and $22-21=1$), 15 of them are primes. (The only non-prime is $22-21=1$.)
Is there an integer for which all the $2n$ sums and differences of its $n$ factor pairs are primes?
Obviously any such integer needs be the even number between a twin prime pair, and needs to be $ = 2$ (mod 4), but that's all I figured out.
Amongst integers less than $10^7$, 462 seems to have the uniquely highest fraction of prime sums/differences of factor pairs, with $15/16$. If there is no integer with a fraction of 1 (the question above), can there be any with a higher fraction than 15/16?