I formulate Henning's excellent answer in its greatest possible generality:
Definition 0. Let $X$ denote a set and $\mathcal{O}$ denote a family of subsets of $X$. Then $D \subseteq X$ is called $\mathcal{O}$-dense iff for every $A \in \mathcal{O} \setminus \{\emptyset\}$, the intersection $D \cap A$ is non-empty. The density of $\mathcal{O}$ is the least cardinality of an $\mathcal{O}$-dense subset. We write $\mathrm{den}(\mathcal{O})$ for the density of $\mathcal{O}$.
Note that:
- $\mathrm{den}(\mathcal{O}) \leq |X|$
- $\mathrm{den}(\mathrm{Open}(\mathbb{R}^n)) = \aleph_0$
Definition 1. Let $X$ denote a set and $\mathcal{F}$ denote a family of subsets of $X$. The repiticity of $\mathcal{F}$ is the least cardinal $\kappa$ such that for all $x \in X$, we have $$|\{A \in \mathcal{F} \mid x \in A\}| \leq \kappa.$$ We write $\mathrm{rep}(\mathcal{F})$ for the repiticity of $\mathcal{F}$.
Note that:
- $\mathrm{rep}(\mathcal{F}) \leq |\mathcal{F}|$
Theorem. Let $X$ denote a set and suppose that $\mathcal{O}$ and $\mathcal{F}$ are families of subsets of $X$ such that $\mathcal{F} \subseteq \mathcal{O} \setminus \{\emptyset\}$. Then: $$|\mathcal{F}| \leq \mathrm{rep}(\mathcal{F}) \cdot \mathrm{den}(\mathcal{O})$$
The proof is now at the end of this answer.
We can now answer your question rather simply.
You ask: can we fit uncountably many nonempty open sets in $\mathbb{R}^n$ such that each point of $\mathbb{R}^n$ is contained in at most finitely many of the sets? If we can answer "no" to the variant of this question in which the phrase "at most finitely many" is replaced by "at most countably many," then we can answer "no" to the original question. But this is equivalent to: does there exist uncountable $\mathcal{F} \subseteq \mathrm{Open}(\mathbb{R}^n) \setminus \{\emptyset\}$ such that $\mathrm{rep}(\mathcal{F}) \leq \aleph_0$? Using our theorem, we see that there does not. For suppose $\mathcal{F} \subseteq \mathrm{Open}(\mathbb{R}^n) \setminus \{\emptyset\}$ satisfies $\mathrm{rep}(\mathcal{F}) \leq \aleph_0$. Then:
$$|\mathcal{F}| \leq \mathrm{rep}(\mathcal{F}) \cdot \mathrm{den}(\mathrm{Open}(\mathbb{R}^n)) \leq \aleph_0 \cdot \aleph_0 = \aleph_0$$
So $\mathcal{F}$ is countable.
Proof. Write $D$ for an $\mathcal{O}$-dense subset of $X$, and assume $|D| = \mathrm{den}(\mathcal{O})$. Define:
$$\mathcal{G} = \{ (d,A) \in D \times \mathcal F \mid d\in A \} $$
There is a projection $\pi_1 : \mathcal{G} \rightarrow \mathcal{F}$ given by $\pi_1(d,A) = A$. This is surjective (use that $\mathcal{F} \subseteq \mathcal{O} \setminus \{\emptyset\}$ and the $\mathcal{O}$-density of $D$). Hence $|\mathcal{F}| \leq |\mathcal{G}|.$
Hence:
$$|\mathcal{F}| \leq |\mathcal{G}| = |\{ (d,A) \in D \times \mathcal F \mid d\in A \}| = \left|\bigoplus_{d:D}\{A \in \mathcal{F} \mid d\in A \}\right| $$
$$= \sum_{d:D} \left|\{A \in \mathcal{F} \mid d\in A \}\right| \leq \sum_{d:D} \mathrm{rep}(\mathcal{F}) = \mathrm{rep}(\mathcal{F}) \cdot |D| = \mathrm{rep}(\mathcal{F}) \cdot \mathrm{den}(\mathcal{O})$$