A nice application of the disjoint union topology is it allows us to deduce the operator version of Kuratowski's closure-complement theorem (see Gardner and Jackson) as a corollary of the original theorem. In its original form, the theorem states that a maximum of 14 distinct subsets can be obtained by repeatedly applying the closure and complement operators to one subset in a topological space. The operator version states that a maximum of 14 distinct operators on a topological space can be obtained by repeatedly composing the closure and complement operators with the identity operator.
Since two operators $o_1$ and $o_2$ are distinct if and only if some subset $A$ satisfies $o_1A\neq o_2A,$ there exist topological spaces in which the number of distinct operators generated by closure and complement is strictly larger than the maximum number of distinct subsets any individual subset generates.* Hence, deducing the operator version from the original theorem requires something extra. That something turns out to be the disjoint union topology.
Suppose $X$ is a topological space in which $n$ distinct operators $o_1,\dots,o_n$ are generated by closure and complement. Thus, for each $1\leq i<j\leq n,$ there exists a subset $A_{ij}\subset X$ such that $o_iA_{ij}\neq o_jA_{ij}.$ Put the disjoint union topology on $$Y=\bigsqcup_{1\leq i<j\leq n}\!\!Y_{ij}$$ where $Y_{ij}=X$ for $1\leq i<j\leq n.$ For any subset $$B=\bigsqcup_{1\leq i<j\leq n}\!\!B_{ij}$$ of $Y$ and $1\leq m\leq n,$ it follows from the definition of the disjoint union topology that $$o_mB=\bigsqcup_{1\leq i<j\leq n}\!\!o_mB_{ij}.$$ Hence, the subset $$A=\bigsqcup_{1\leq i<j\leq n}\!\!A_{ij}$$ of $Y$ satisfies $o_iA\neq o_jA$ for all $1\leq i<j\leq n.$ It follows that $n\leq14$ by the closure-complement theorem (for subsets).
The operator version is usually proved directly (from which the subset version follows immediately), but the above construction illustrates that we can always find some subset in some space that distinguishes all the operators that get generated from an initial collection built from closure, complement, union, and intersection.
*When these two numbers are equal Gardner and Jackson call the space full.