Q: Is number of the form $$\displaystyle 2^{M^N}+M^{N^2}$$ always composite for $M,N$ odd primes?
I observed that:
If $M=N$ then this number is absolutely a composite, because it satisfies the identity $a+b \mid a^k+b^k$ if k is odd numbers.
If $M \equiv 1 \pmod 3$ then this number is always composite, because it divisible by $3$.
I see that $2^{2c+1} \pmod 3=2$ for all natural numbers $c$, and $p^t \pmod 3=1$ if $p$ is a prime of type $1 \pmod 3$, then it is clear that $2^{M^N}+M^{N^2}$ divisible by $3$ if $M$ prime number of type $1 \pmod 3$.
I have checked it exhaustively, and I always found it composites.