Hint:
use: $a\sqrt{b}=\dfrac{a}{|a|} \sqrt {a^2b}= \mbox{sign}(a)\sqrt {a^2b}$
Here $|a|$ is the absolute value of $a$, so that $\dfrac{a}{|a|}= 1$ if $a>0$ and $\dfrac{a}{|a|}= -1$ if $a<0$. This same result can be represented wit the function "sign (a)" that is simply the sign of $a$.
The use of this function is very important when we work with radicals because the square of a number is always positive, so, squaring $a$ we can forget that the basis of the square was negative.
In you case $a=4$, so sign$(4)=+1$ and you have no problem writing:
$$
4 \sqrt{5}=\sqrt{16 \times 5}
$$
but if you have , e.g. : $a=-4$ the correct result is:
$$
-4 \sqrt{5}=-\sqrt{16 \times 5}
$$