Mr. David Norata of south Borneo conjectures that $16^{317}+1$ is the last/largest semi-prime of the form $16^n+1$. But he didn't give any clue why he is so sure about this, he just said that he has a rough proof.
Note that $16^n+1$ can be a semi-prime if and only if $n$ is a prime number, and some values of $n$ for which $16^n+1$ is a semi-prime are $3,5,7,23,37,89,149,173,251,307, 317, \ldots$.
Can you prove or disprove Mr. Norata's conjecture?