Consider a generator $x$ of the singular homology group $H_3(S^3)$. I think of this (perhaps wrongly?) as something like the identity on $S^3$, cut up into simplices. Now we have the Hopf fibration $\eta: S^3 \to S^2$, which gives us $\eta_*x \in H_3(S^2) = 0$. Thus $\eta_*x$ is a boundary. Of what is it the boundary?
If this is silly or uninteresting, why is it so?