Recently I have read the proof of the Jordan Curve Theorem in Munkres' Topology, I wonder whether there are some generalizations and corollaries on this theorem as follows:
I know any simple closed curve separate $\mathbb R^2$ into two components, one is bounded and the other one is unbounded. How to prove that the bounded component is simply connected and the unbounded component is homeomorphic to $\mathbb R^2-\{0\}$?
Can the theorem be generalized into higher dimension? Given a simple closed curve in $\mathbb R^n$, does there exist $U\in\mathbb R^n$ such that $U$ is a simply connected 2-manifold whose boundary is exactly the curve?
I believe the first question would be a simple consequence of Jordan Curve Theorem (although I cannot figure out a proof, can any one give me one if possible?). However I am not quite sure whether my second question is even related to the JCT.