Your question about drawing a $4,6$ or a $6,4$ is a good one.
I'd break it down into two cases: one with the cards the same, the other with cards different.
If the cards are the same, first choose the face value of the card ($13$) then choose the two suits ($_4C_2 = 6$). So there are $13 \cdot 6 = 78$ possible ways to draw a pair. Of these, two $5$'s through two $8$'s satisfy your criterion: $4$ values $\times 6$ suit combinations for each $= 24$ possibilities.
If the cards are different, first choose the two face values ($_{13}C_2 = 78$) then choose the suit for each card ($16$). So there are $78 \cdot 16 = 1248$ ways to draw two different cards.
(Note: $_{52}C_2 = 1326 = 78 + 1248,$ so we've indeed accounted for all possibilities.)
Counting the number of possibilities with the sum between $10$ and $16$ with two different cards is bookkeeping. I'll start with the larger card, and work my way up from the bottom with the smaller cards to go through the possibilities methodically. I'll also not write a higher card second, because that would double-count.
$A2, A3, A4, A5$
$K2, K3, K4, K5, K6$
$Q2, Q3, Q4, Q5, Q6$
$J2, J3, J4, J5, J6$
$T2, T3, T4, T5, T6$
$92, 93, 94, 95, 96, 97$
$82, 83, 84, 85, 86, 87$
$73, 74, 75, 76$
$64, 65.$
I count $42$ combinations for the values. Since either card can be any suit, that's $42\cdot 16 = 672$ possible combinations.
Now we're basically done:
$$P = \frac{672+24}{1326} \approx 0.525.$$