JKnecht's answer is partially wrong, it is true that
$$\frac{\partial u_1}{\partial x}(x, y) =\frac{\partial u}{\partial x}(x, -y)$$
$$\frac{\partial v_1}{\partial x}(x, y) =-\frac{\partial v}{\partial x}(x, -y)$$
Let's prove the first one, for example. Observe that $u_1(x, y) = u(c(x, y)) $, with $c(x, y) = (c_1(x, y),c_2(x, y))= (x, -y) $ is the complex conjugate.
Applying chain rule, we get:
$$\frac{\partial u_1}{\partial x}(x, y) = \frac{\partial(u\circ c) }{\partial x}(x, y) = \frac{\partial u}{\partial x}(c(x, y)) \frac{\partial c_1}{\partial x}(x, y) + \frac{\partial u}{\partial y}(c(x, y)) \frac{\partial c_2}{\partial x}(x, y) =\frac{\partial u}{\partial x}(x, -y) .$$
We have used that $\frac{\partial c_1}{\partial x} = 1, \frac{\partial c_2}{\partial x} = 0$.
But the partial derivatives w. r. t. $y$ are related by another formula:
$$\frac{\partial u_1}{\partial y}(x, y) =\frac{\partial (u\circ c)}{\partial y}(x, y)=\frac{\partial u}{\partial x}(c(x, y)) \frac{\partial c_1}{\partial y}(x, y) + \frac{\partial u}{\partial y}(c(x, y)) \frac{\partial c_2}{\partial y}(x, y) =-\frac{\partial u}{\partial y}(x, -y) . $$
We have used that $\frac{\partial c_1}{\partial y} = 0,\frac{\partial c_2}{\partial y} = -1$.
Similarly, one proves that:
$$\frac{\partial v_1}{\partial y}(x, y) =\frac{\partial v}{\partial y}(x, -y) . $$
In conclusion, the partial derivatives must be compared at different points. This still implies the CR equations.
$$ \frac{\partial u_1}{\partial x}(x, y) =\frac{\partial u}{\partial x}(x, -y)= \frac{\partial v}{\partial y}(x, -y)= \frac{\partial v_1}{\partial y}(x, y). $$
We have used that $u, v$ verify Cauchy-Riemann at the point $(x, -y) $, and the previous equalities.
Same goes for the other equation:
$$ \frac{\partial u_1}{\partial y}(x, y) =-\frac{\partial u}{\partial y}(x, -y)= \frac{\partial v}{\partial x}(x, -y)= -\frac{\partial v_1}{\partial x}(x, y). $$
EDIT: Another easy way of showing this goes by seeing that the complex conjugate preserves angles (but not orientations), so clearly $c(f(c(x, y))$ preserves angles (because $f$ also does) AND orientations (because $f$ preserves orientations and $c$ reverses them twice, so the composition preserves them). Every map preserving orientations and angles is holomorphic.
EDIT2: Proof of the equality of derivatives w. r. t. $y$. Recall that $v_1= -v\circ c$:
$$\frac{\partial v_1}{\partial y}(x, y) =-\frac{\partial (v\circ c)}{\partial y}(x, y)=-\frac{\partial v}{\partial x}(c(x, y)) \frac{\partial c_1}{\partial y}(x, y) - \frac{\partial v}{\partial y}(c(x, y)) \frac{\partial c_2}{\partial y}(x, y) =\frac{\partial v}{\partial y}(x, -y) . $$
We have used that $\frac{\partial c_1}{\partial y} = 0,\frac{\partial c_2}{\partial y} = -1$.