Here’s another variation on the idea of using compactifications to avoid algebraic topology: $\Bbb R\times[0,1]$ has a two-point compactification, but $\Bbb R^2$ does not.
The two-point compactification of $\Bbb R\times[0,1]$ is pretty evident. Suppose that that $\Bbb R^2$ has a compactification $X=\{p,q\}\cup\Bbb R^2$, where $p\ne q$. Let $U$ and $V$ be disjoint open nbhds of $p$ and $q$; $K=\Bbb R^2\setminus(U\cup V)$ is a compact subset of the plane. Let $G=U\cap\Bbb R^2$ and $H=V\cap\Bbb R^2$; $G$ and $H$ are open in $\Bbb R^2$ and partition $\Bbb R^2\setminus K$.
$K$ is compact, so let $r_0=\max\{\|x\|:x\in K\}$. For each $r>r_0$ let $C_r$ be the circle of radius $r$ centred at the origin. $C_r$ is connected, so for each $r\ge r_0$ we must have $C_r\subseteq G$ or $C_r\subseteq H$. Let $I_G=\{r>r_0:C_r\subseteq G\}$ and $I_H=\{r>r_0:C_r\subseteq H\}$. Each $C_r$ is compact, so $I_G$ and $I_H$ are open subsets of the connected set $(r_0,\to)$; without loss of generality $I_G=(r_0,\to)$ (and $I_H=\varnothing$). It follows that $H$ is a bounded open set in $\Bbb R^2$ and hence that $W=X\setminus\operatorname{cl}_{\Bbb R^2}H$ is an open nbhd of $q$ in $X$. But then $V\cap W=\{q\}$ is open in $X$, and $q$ is isolated, which is impossible.