Something as nasty as this is only going to be solvable if it's the derivative of a nasty composite. My first guess is it's the derivative of $\sin{\csc{\csc{x}}}$ (I took the part with most compositions and wrote down the integral of the $\cos$ part), so let's differentiate and see what happens:
\begin{align} \frac{d}{dx} \sin{\csc{\csc{x}}} &= (\cos{\csc{\csc{x}}}) \frac{d}{dx} \csc{\csc{x}} \\
&= -(\cos{\csc{\csc{x}}}) (\csc{\csc{x}}\cot{\csc{x}})\frac{d}{dx} \csc{x} \\
&= +(\cos{\csc{\csc{x}}}) \frac{\cos{\csc{x}}}{\sin^2{\csc{x}}} (\csc{x}\cot{x}) \\
&= (\cos{\csc{\csc{x}}}) \frac{\cos{\csc{x}}}{\sin^2{\csc{x}}} \frac{\cos{x}}{\sin^2{x}},
\end{align}
which of course is exactly the integrand. Hence the integral is
$$ \int_{\pi/3}^{\pi} \frac{d}{dx} \sin{\csc{\csc{x}}} \, dx, $$
from which it's easy to finish. (Note that although the integrand behaves quite badly at $x=\pi/2$, we can still find the continuous antiderivative we needed for the Fundamental Theorem of Calculus to work.)