I tried using the following approach:
$$x=2222^{5555}+5555^{2222} = (2222^5)^{1111}+(5555^2)^{1111}$$
Now we know $(x^n+y^n)$ is divisible by $(x+y)$ for odd natural number $n$. So,
$$x=(2222^5+5555^2)k,\ k\in N$$
$$x=(1111^2)(32\cdot1111^3+25)k$$
The term in parentheses was found to be $54165190296027657$, which is divisible by $7$. Thus $7 | x$.
Another method (edit):
We can also write $$2222^{5555} = (7\times 317+3)^{5555} = 7p+3^{5555}$$ Similarly $$5555^{2222}=(793\times7+4)^{2222} = 7q+4^{2222}$$
So we have $$x=7(p+q)+(3^5+4^2)r$$ Here we have $3^5+4^2$ is divisible by $7$. So $x$ is also divisible by $7$.
But is there a simple way without multiplication of large numbers? Thank you!