This question was asked on Quora, and I thought I'd try to post a question on MSE to get it answered (because you know, you guys tend to be smarter than them :P)
What is$$\begin{vmatrix}\binom 00 & \binom 10 & \cdots & \binom n0\\\binom 10 & \binom 11 & \cdots & \binom n1\\\vdots & \vdots & \ddots & \vdots\\\binom n0 & \binom n1 & \cdots & \binom nn\end{vmatrix}$$equal to?
If you run the first few values of $n$ in Mathematica, you get a particularly arbitrary-looking sequence$$1,0,-1,8,-71,656,-4816,1920,168784,43920880$$Which doesn't have a particular sequence in oeis. Do you guys have any other insights on this?
I'm also well aware that this problem may not actually have a simplification.