Here is one result, which answers your Question 3:
Theorem [EGA IV$_{3}$, Cor. 15.2.3]. Let $Y$ be a locally noetherian scheme, and let $f \colon X \to Y$ be a morphism locally of finite type. Let $x \in X$ be a point with image $y = f(x)$. Suppose the following conditions hold:
- the morphism $f$ is universally open at the generic point of every irreducible component of $f^{-1}(y)$ containing $x$;
- the fiber $f^{-1}(y)$ is geometrically reduced (over $\kappa(y)$) at $x$; and
- the local ring $\mathcal{O}_{Y,y}$ is reduced.
Then, $f$ is flat at the point $x$.
This says that universally open morphisms that are not flat must have some non-reducedness somewhere, either in the fibers or on the base, thereby answering your Question 1, at least if you strengthen "open" to "universally open." There are surely examples of open but not universally open morphisms, too, though.
Arrow asked two more questions in the comments.
- My intuition for a non-reduced base is that for the morphism $f$ to be flat, the morphism should look like a restriction of a nice family on a larger base space. So you can't expect flatness to be captured purely topologically. Depending on your taste, non-reduced fibers are less geometric, since this won't happen if $X$ is smooth and everything is over a field of characteristic $0$ by generic smoothness.
- Again depending on your taste, open but not universally open morphisms are less geometric, since they cannot happen if the base is reduced and normal [EGA IV$_{3}$, Cor. 14.4.9]. I find this MathOverflow question insightful. In particular, it mentions an example of an open morphism which is not universally open, hence not flat; there is another example [EGA IV$_{3}$, Rem. 14.3.9(i)] in the comments.