Up to $12\times 12$ is good. $12$ has lots of factors. Past that, the next few numbers don't have so many factors. Why do factors matter?
I have a small gig tutoring 6th and 7th grade "at risk" students. Most of them can't add fractions. The first hurdle in adding fractions is that given
$$\frac{5}{42} +\frac{7}{48}$$
they need to find a common denominator. Since they don't have their multiplication facts memorized, the numbers $42$ and $48$ mean nothing
special to them. (This is my answer to people who say, "We have
calculators now, so why memorize multiplication tables?" Answer:
Because when you see $42$, you need to think $6\times 7$, or you'll
play hell trying to add fractions.)
So being able to quickly factor smallish denominators is a useful
skill. Working the above addition of fractions is extremely painful
if one has to stop and tediously factor $42$ and then $48$ and then
figure out what the LCD is.
(Alternatively, the students can multiply the first fraction by $\frac{48}{48}$ and the second fraction by $\frac{42}{42}$. But then we have the same problem.
The answer is a fraction in unreduced form, and they still have to factor.)
(Smooth segue into rant:) This is what happens every time someone at one level of math decides that some bit of math isn't useful anymore. Logarithms are the classic. "Now that we have calculators, we no longer need log's, so let's cut them out of the high school curriculum." Now our Calc 1 students don't know log's and ask questions like "I got $\ln 1/2$ but the back of the book says $-\ln 2,$ what did to wrong?" Answer: You went to the wrong high school.