Two of the roots sum to 4. All 4 roots sum to 8. This means that the other two roots must also sum to 4.
If this polynomial had rational roots, they would have to be in the set $\{\pm1,\pm5\}$
By what we have above we might try $x=-1, x = 5$ alas these do not work.
We could factor the polynomial like so:
$(x^2 - 4x + A)(x^2 -4x + B)\\
A+B = 5\\
AB = 5$
And solve for $A,B$
Or we might try
$(x -2 + a)(x-2-a)(x-2 + b)(x-2-b)$
Then substituting
$y = x-2\\x = y+2$
Into the original polynomial
$(y+2)^4 - 8(y+2)^3 + 21(y+2)^2 -20(y+2) + 5\\
y^4 - 3y^2+1\\
y^2 = \frac 32 \pm \sqrt 2\\
y = \pm \sqrt {\frac 32 \pm \sqrt 2}\\
x = 2\pm \sqrt {\frac 32 \pm \sqrt 2}$