As you have $n\in \mathbb{N}$, induction like in Nameless's answer seems to be the most natural way to prove your result.
However, here is a prove using properties of the $\Gamma$ function:
The binomial coefficient can be expressed in terms of the $\Gamma$ function as
$$\binom{a}{b} = \frac{\Gamma(a+1)}{\Gamma(b+1) \Gamma(1+a-b)}.$$
Write
$$C_1(n)=-\frac{1}{2}\binom{1/2}{n}(-4)^n = - \frac{(-4)^n \overbrace{\Gamma(3/2)}^{\sqrt\pi/2}}{2\Gamma(3/2-n) \Gamma(n+1)}
= \frac{(-1)^{n+1} \sqrt\pi 4^{n-1}}{\Gamma(3/2-n) \Gamma(1+n)}$$
and [using the duplication formula $\Gamma(2z) =\Gamma(z) \Gamma(z+1/2)2^{2z-1}/\sqrt\pi$ with $z=n-1/2$]
$$C_2(n)=\frac{1}{n}\binom{2n-2}{n-1} = \frac{\overbrace{\Gamma(2n-1)}^{\Gamma[2 (n-1/2)]}}{n \Gamma(n)^2}
=\frac{4^{n-1}\Gamma(n-1/2)}{\sqrt\pi \,\Gamma(n+1)}.$$
Taking the ratio yields
$$\frac{C_2(n)}{C_1(n)}=\frac{(-1)^{n+1}}{\pi} \Gamma(n-1/2) \Gamma(3/2-n).$$
Now use the reflection formula$$\Gamma(z)\Gamma(1-z) = \frac{\pi}{\sin(\pi z)}.$$
Setting $z=n-1/2$, we obtain
$$\frac{C_2(n)}{C_1(n)}= \frac{(-1)^{n+1}}{\sin(\pi n -\pi/2)}
= \frac{(-1)^n}{\cos(\pi n)} =1.$$