From a formal point of view, the solution is given in terms of the generalized Lambert function. You could be interested by this paper which starts with the problem of
$$e^{-c x}=a_0\frac{x-t}{x-s}$$ For your case, it would be $c=-\log(2)$, $a_0=-2$, $t=2$, $s=-4$.
You also could be interested by this very recent paper about Taylor series for the generalized Lambert functions.
However, from a practical point of view (except in special case where the solutions are "obvious" using graphics), consider numerical methods.
For the fun of it, let us change the problem to
$$2^x(5-x)=2x+3$$ and consider that you look for the zero of
$$f(x)=2^x(5-x)-2x-3$$ with derivatives
$$f'(x)=2^x (5\log (2)-x \log (2)-1)-2$$
$$f''(x)=-2^x \log (2) ((x-5) \log (2)+2)$$
Using Lambert function, the first derivative cancels at two points
$$x_1=\frac{W_{-1}\left(-\frac{e}{16}\right)+5 \log (2)-1}{\log (2)}\approx -0.487$$
$$x_2=\frac{W\left(-\frac{e}{16}\right)+5 \log (2)-1}{\log (2)}\approx 3.255$$
The second derivative test shows that $x_1$ corresponds to a minimum $(f''(x_1)\approx 0.892)$ and $f(x_1)\approx 1.889$. Similarly, $x_2$ corresponds to a maximum $(f''(x_2)\approx -5.231)$ and $f(x_2)\approx 7.149$. So, there is only one root $x > x_2$.
By inspection, $f(4)=5$ and $f(5)=-13$. Let us start Newton method using, as an initial guess, $x_0=4.5$. This would generate the following iterates
$$\left(
\begin{array}{cc}
n & x_n \\
0 & 4.500000000 \\
1 & 4.459113666 \\
2 & 4.457758000 \\
3 & 4.457756552
\end{array}
\right)$$ which is the solution for ten significant figures.