Suppose $a,b,c$ are integers, with $a,b,c \ge 4$, such that
$$4abc=(a+3)(b+3)(c+3)$$
Assume $a\le b \le c$.
Suppose $b \ge 6$.
Then also $c\ge 6$, so $c+3 \le \bigl({\large{\frac{3}{2}}}\bigr)c$, hence
\begin{align*}
&4abc\le(a+3)(b+3)\bigl({\small{\frac{3}{2}}}\bigr)c\\[4pt]
\implies\;&8ab\le 3(a+3)(b+3)\\[4pt]
\implies\;&5ab\le 9a + 9b + 27\\[4pt]
\implies\;&b(5a-9)\le 9a+27&&(*\!)\\[4pt]
\implies\;&a(5a-9) \le 9a+27\\[4pt]
\implies\;&5a^2-18a-27\le 0\\[4pt]
\implies\;&a < 5\\[4pt]
\implies\;&a=4\\[4pt]
\implies\;&11b\le 63&&\text{[by substituting $a=4$ into$\;(*\!)$]}\\[4pt]
\implies\;&b < 6\\[4pt]
\end{align*}
contradiction.
It follows that $b\le 5$.
Consider cases . . .
If $(a,b) = (4,4)$, then subsituting $a=4,b=4$ in the main equation yields
$c={\large{\frac{49}{5}}}$, contradiction.
If $(a,b) = (4,5)$, then subsituting $a=4,b=5$ in the main equation yields
$c=7$, which gives the solution triple $(a,b,c)=(4,5,7)$.
If $(a,b) = (5,5)$, then subsituting $a=5,b=5$ in the main equation yields
$c={\large{\frac{16}{3}}}$, contradiction.
Thus, up to a permutation of the variables, the only solution is $(a,b,c)=(4,5,7)$, so $a+b+c=16$.