OK, first of all I am inclined to say that though expanding $\mathbf x(s)$ in terms of the Frenet-Serret frame,
$\mathbf x = \lambda T + \mu N + \nu B, \tag 1$
as our OP user30523 has done, though at time-honored technique which often bears fruit--as in fact it does here, see my comments below--is a little more complicated than what is needed in the present context; so what I'll do is put forth my method for solving this problem--which incidentally only needs the Frenet-Serret equation $T = \kappa N$, as I will now demonstrate, and then offer a few comments on our OP's work.
I assume the curve $\mathbf x(s)$ is parametrized by its arc-length, which I take to be $s$; such usage is consistent with our OP's equation $\dot{\mathbf x}(s) = T(s)$, which only holds for unit-speed, arc-length parametrized curves.
From
$\mathbf x(s) \cdot \mathbf x(s) = R^2, \; \text{a constant}, \tag 2$
we obtain, upon differentiation with respect to $s$,
$T(s) \cdot \mathbf x(s) = \dot{\mathbf x}(s) \cdot \mathbf x(s) = 0, \tag 3$
and taking $d/ds$ once more we derive the equation:
$\dot T(s) \cdot \mathbf x(s) + 1 = \dot T(s) \cdot \mathbf x(s) + T(s) \cdot T(s) = \dot T(s) \cdot \mathbf x(s) + T(s) \cdot \dot {\mathbf x}(s) = 0. \tag 4$
The curvature $\kappa(s)$ is defined via the Frenet-Serret equation
$\dot T(s) = \kappa(s) N(s), \; \vert N(s) \vert = 1, \; \kappa(s) > 0; \tag 5$
also,
$\mathbf x(s) = R \mathbf n(s), \tag 6$
where $\mathbf n(s)$ is the unit normal to the sphere at point $\mathbf x(s)$; we substitute (5) and (6) into (4):
$\kappa(s) N(s) \cdot R \mathbf n(s) + 1 = 0, \tag 7$
or
$\kappa(s) N(s) \cdot \mathbf n(s) = -\dfrac{1}{R}; \tag 8$
we take absolute values, recalling $\kappa(s) > 0$:
$\kappa(s) \vert N(s) \cdot \mathbf n(s) \vert = \dfrac{1}{R}; \tag 9$
since
$\vert \mathbf n(s) \vert = \vert N(s) \vert = 1, \tag{10}$
we have by Cauchy-Schwarz that
$\vert \mathbf n(s) \cdot N(s) \vert \le \vert \mathbf n(s) \vert \vert N(s) \vert = 1, \tag{11}$
whence
$\kappa(s) = \dfrac{1}{\vert \mathbf n(s) \cdot N(s) \vert R} \ge \dfrac{1}{R}, \tag{12}$
as was to be proved. $\mathbf{OE\Delta}$.
A Few Remarks: Our OP's equation
$\ddot{\mathbf x}(s) \cdot \mathbf x(s) = 0 \tag{13}$
is erroneous, and does not follow from (3), as is shown in the preceding derivation; the correct consequence is (4), from which the desired result is readily reached.
Our OP's attempt, based upon
$\mathbf x = \lambda T + \mu N + \nu B \tag{14}$
bears further scrutiny. We have:
$T = \dot{\mathbf x} = \dot \lambda T + \lambda \dot T + \dot \mu N + \mu \dot N + \dot \nu B + \nu \dot B; \tag{15}$
using the complete set of Frenet-Serret equations,
$\dot T = \kappa N, \tag{16}$
$\dot N = -\kappa T + \tau B, \tag{17}$
$\dot B = -\tau N, \tag{18}$
we may re-write (15) in the form
$T = \dot{\mathbf x} = \dot \lambda T + \lambda \kappa N + \dot \mu N + \mu (-\kappa T + \tau B) + \dot \nu B -\nu \tau N$
$= (\dot \lambda - \mu \kappa)T + (\dot \mu + \lambda \kappa - \tau \nu)N + (\dot \nu + \mu \tau)B, \tag{19}$
from which I draw
$\dot \lambda - \mu \kappa = 1, \tag{20}$
$\dot \mu + \lambda \kappa - \tau \nu = 0, \tag{21}$
$\dot \nu + \mu \tau = 0; \tag{22}$
we further compute
$\lambda \dot \lambda + \mu \dot \mu + \nu \dot \nu = \lambda \dot \lambda + \mu \dot \mu + \nu \dot \nu - \lambda \mu \kappa + \mu \lambda \kappa - \mu \tau \nu + \nu \mu \tau$
$= \lambda (\dot \lambda - \mu \kappa) + \mu (\dot \mu + \lambda \kappa - \tau \nu) + \nu (\dot \nu + \mu \tau) = {\mathbf x} \cdot \dot {\mathbf x} = 0, \tag{23}$
which may also be derived by observing that, from (14),
$\lambda^2 + \mu^2 + \nu^2 = \mathbf x \cdot \mathbf x = R^2, \tag{23}$
and then differentiating with respect to $s$.