Consider a function $f:(\Bbb R,\mathcal A_1)\to (\Bbb R,\mathcal A_2)$, where $\mathcal A_i$'s are the $\sigma$-algebras on $\Bbb R$. We want nice functions to be measurable and I hope you'd agree that continuous functions should be considered nice.
The $\sigma$-algebra we should impose on $\mathcal A_2$ (the target space) that is compatible with the usual topology on $\Bbb R$ is the Borel $\sigma$-algebra $\mathcal B$ since it is the $\sigma$-algebra generated by $\tau_{\Bbb R}$, the topology of $\Bbb R$.
On the other hand, while it is possible to let $\mathcal A_1=\mathcal B$ (this is enough if we merely require that all continuous functions be measurable), it is more convenient if we can say that "all subsets of null sets are null" because the adjective "almost everywhere" is linked to the $\sigma$-algebra $\mathcal A_1$.
Hence, we usually take the Lebesgue $\sigma$-algebra $\mathcal A_1=\mathcal M$, the completion of $\mathcal B$, as the $\sigma$-algebra on our domain.
PS. Here's my answer to a related question regarding why choosing $\mathcal A_1 = \mathcal A_2 = \mathcal B$ is sometimes better than $\mathcal M-\mathcal B$.