Another way to view your ring is as $R[x]$ localised at the multiplicative set $S = \{r\cdot x^k\mid r\in R^\times, k\in \Bbb N\}$. Really, it's just localised at the set $\{1, x, x^2, \ldots\}$, but including the units of $R$ allows us to skip a step.
I claim that this $S$ is saturated, which is to say if $f, g\in R[x]$ are such that $fg\in S$, then $f, g\in S$. This is not difficult to see:
- $fg$ is a monomial, so $f$ and $g$ must be monomials
- $fg$ has an invertible coefficient, so $f$ and $g$ must have invertible coefficients
which is to say $f, g\in S$.
Why does this matter? Because if you localise by a saturated set $S$, then that saturated set contains all elements that become invertible in the localisation.
Let $\frac fs\in S^{-1}R[x]$ be invertible. Then there is a $\frac gt\in S^{-1}R[x]$ such that $\frac fs\cdot \frac gt = \frac11$. By definition of localisation, this means that
$$
fg\cdot 1 = st\cdot 1
$$
(The absence of zero divisors in $R[x]$ means we can simplify the definition of equality in a localisation to this.) Since $st\in S$ because $S$ is multiplicatively closed, we also have $fg\in S$. However, this implies that $f\in S$. So $\frac fs$ is a fraction where both he numerator and the denominator are in $S$, and because of the general form of elements in $S$, this means that $\frac fs$ is either equal to a fraction of the form $\frac{1}{rx^k}$ or to a fraction of the form $\frac{rx^k}1$ where $r\in R^\times, k\in \Bbb N$.