Hint:
A parabola is of the form $y = ax^2 + bx + c$
We are told that it passes through the points $(1,2),(2,1)$ and $(3,4)$. (I suggest ignoring $(4,3)$ for now and revisit it later)
That means that plugging in those $x$ and $y$ values, the fact that it passes through $(\color{blue}{1},\color{red}{2})$ implies that $\color{red}{2} = a\cdot \color{blue}{1}^2 + b\cdot \color{blue}{1} + c$. Similarly we can find the equations that are implied by the parabola passing through the other points.
We have then this system of equations:
$$\begin{cases}2 = a + b + c\\1 = 4a + 2b + c\\ 4 = 9a + 3b + c\\\end{cases}$$
Now... this is a system of three linear equations and three unknowns which can by solved by standard means.
(Now, consider including $(4,3)$ as well. Does this affect the answer?)