Let $R_1 \subset R_2$ be two integral domains. If $f \in R_1[x]$ is a polynomial which factors as $gh$ with $g,h \in R_2[x]$, then the coefficients of $g$ and $h$ are integral over $R_1$.
I tried a bunch of stuff, but didn't really get anywhere without using the extra assumption of it being a UFD/PID/Dedekind domain (which is not provided)