I think you mean $\int\limits_{\mathbb{R}^n}\frac{dx_1...dx_n}{|x|^p}$. You could try to make spherical change of variables (in both cases). Other ways - Kronrod-Federer theorem (private case - representation as integral over sphere) or distributional function $F_{|x|}(t)$ if you know what it is. After all: in the first case integral diverges for any $p$, in the second converges iff $p<n$.
Look, we have $x=(x_1,...,x_n) \in \mathbb{R}^n$. Let $r \in \mathbb{R}$ and $\phi=(\phi_1,...,\phi_{n-1}) \in \mathbb{R}^{n-1}$. We have spherecal change $x=\Phi(r,\phi)$ given by: $$x_1=r\cos(\phi_{n-1})\cos(\phi_{n-2})\cdot...\cdot\cos(\phi_2)\cos(\phi_1),$$ $$x_2=r\cos(\phi_{n-1})\cos(\phi_{n-2})\cdot...\cdot\cos(\phi_2)\sin(\phi_1),$$
$$x_2=r\cos(\phi_{n-1})\cos(\phi_{n-2})\cdot...\cdot\sin(\phi_2),$$
$$.............$$
$$x_{n-1}=r\cos(\phi_{n-1})\sin(\phi_{n-2}),$$
$$x_{n}=r\sin(\phi_{n-1}).$$
$G=\{(r,\phi):~r\in(0,+\infty),~ \phi_1 \in (-\pi,\pi),~ \phi_i \in (-\pi/2,\pi/2)$ if $ i>1\}$. Then $\Phi(G)=\mathbb{R}^n \setminus \{x:x_1 \leq 0, x_2=0\}=Y$ and $\Phi:G \longrightarrow Y$ is diffeomorfism with $\det \Phi^{'}=r^{n-1}\cos^{n-2}(\phi_{n-1})\cdot...\cdot\cos^2(\phi_3)\cos(\phi_2)$.
Note that $|x|=r$.
Now we can rewrite your integral as follows: $$\int\limits_{\mathbb{R}^n}\frac{dx_1...dx_n}{|x|^p}=\int\limits_{G}\frac{\det \Phi^{'}}{r^p}drd\phi_{n-1}...d\phi_1=\int\limits_{G}\frac{r^{n-1}\cos^{n-2}(\phi_{n-1})\cdot...\cdot\cos^2(\phi_3)\cos(\phi_2)}{r^p}drd\phi_{n-1}...d\phi_1=$$ $$=\underbrace{\Bigg(\prod\limits_{i=2}^{n-1}\int\limits_{-\pi/2}^{\pi/2}\cos^{i-1}(\phi_i)d\phi_i\Bigg)}_{V_n \in (0,+\infty)}\cdot\int\limits_{0}^{+\infty}r^{n-1-p}dr.$$ The last integral diverges for any p.
In the second case we have $$\int\limits_{\mathbb{R}^n}\frac{dx_1...dx_n}{|x|^p}=V_n\int\limits_{0}^{\alpha}r^{n-1-p}dr,$$ which converges iff $p<n$.
Addition: $V_n$ is Hausdorf measure of $(n-1)$-dimentional shpere with radius = 1.