Partial Answer:
$\newcommand{\op}[2]{ \left\langle #1 ,\, #2 \right\rangle }$
$\newcommand{\rel}[1]{ \mathcal{#1} }$
Let $a = \op{a_1}{a_2}$ and $b = \op{b_1}{b_2}$.
We can redefine $\rel{R'}$:
\begin{align}
\op{a}{b} \in \rel{R'} \iff \{ a ,\, b \} \subseteq \rel{R}
\end{align}
The order of elements in a set does not matter, i.e. $\{ a ,\, b \} = \{ b ,\, a \}$, so the relation $\rel{R'}$ is always symmetric.
Because $\rel{R}$ is reflexive, we have $\forall x \in A \left( \op{x}{x} \in \rel{R} \right)$.
Let $a = b = \op{x}{x}$, obviously $\{ a ,\, b \} = \{ a ,\, a \} = \{ a \} \subseteq \rel{R}$, therefore $\op{a}{a} \in \rel{R'}$, i.e. $\rel{R'}$ is reflexive.
Let $x = \op{x_1}{x_2},\; y = \op{y_1}{y_2},\; z = \op{z_1}{z_2}$, and $\{ x,\, y,\, z \} \subseteq \rel{R}$.
\begin{align}
\{ x ,\, y \} \subseteq \rel{R} &\implies \op{x}{y} \in \rel{R'} \\
\{ y ,\, z \} \subseteq \rel{R} &\implies \op{y}{z} \in \rel{R'} \\
\{ x ,\, z \} \subseteq \rel{R} &\implies \op{x}{z} \in \rel{R'}
\end{align}
Therefore, $\rel{R'}$ is always transitive.
To prove $\rel{R'}$ is antisymmetric, we have to prove $\rel{R'} \cap \rel{R'}^{-1} \subseteq \Delta x$, where $\Delta x = \{ \op{x}{x} :\: x \in A \}$.
Because $\rel{R'}$ is always symmetric, $\rel{R'} = \rel{R'}^{-1}$. Then we have to prove $\rel{R'} \cap \rel{R'}^{-1} = \rel{R'} \subseteq \Delta x$. Meanwhile, $\rel{R'}$ is reflexive, so $\Delta x \subseteq \rel{R'}$. Therefore, to prove $\rel{R'}$ is antisymmetric, we have to prove $\rel{R'} = \Delta x$, or $$\forall x,\,y \in A \left( \begin{array}{c} x = y \iff \op{x}{y} \in \rel{R'} \\ x \neq y \iff \op{x}{y} \notin \rel{R'} \end{array} \right)$$
Furthermore,
$$\forall x,\,y \in A \left( \begin{array}{c} x = y \iff \{ x,\,y \} \subseteq \rel{R} \\ x \neq y \iff \{ x,\,y \} \nsubseteq \rel{R} \end{array} \right)$$
For all $x_1,\,x_2 \in A$, let $x = \op{x_1}{x_2},\; y = \op{x_2}{x_1}$. Obviously, $x = y$ when $x_1 = x_2$, $x \neq y$ when $x_1 \neq x_2$.
Because $\rel{R}$ is antisymmetric, assumming $x_1 \neq x_2$ and $x = \op{x_1}{x_2} \in \rel{R}$, we can get $y = \op{x_2}{x_1} \notin \rel{R}$.
Now we have $x \neq y \implies \{ x,\, y \} \nsubseteq \rel{R}$.
Assume $\{ x,\, y \} \nsubseteq \rel{R}$, then $ x \notin \rel{R} \lor y \notin \rel{R}$, i.e. $ \op{x_1}{x_2} \notin \rel{R} \lor \op{x_2}{x_1} \notin \rel{R}$ holds. Because $\rel{R}$ is reflexive, $\op{x_1}{x_1} \in \rel{R}$ and $\op{x_2}{x_2} \in \rel{R}$. Now we get $x_1 \neq x_2$, i.e. $\{ x,\, y \} \nsubseteq \rel{R} \implies x \neq y$.
Therefore, $\rel{R'}$ is antisymmetric.
All in all, $\rel{R'}$ is an ordering relation when $\rel{R}$ is one.