According to google, it's when $f'(x)$ doesn't exist. I was given the following functions:
\begin{align} y & = -\tfrac 1 3x^3 -4x + 16x \\[6pt] y & = xe^{-x/4} \\[6pt] y & = -\cos(x-4) \\[6pt] y & = -x^2 + 8x \end{align}
I was able to automatically rule out the first and last because they're polynomials. Then I was stuck with the middle two. But they both have first derivatives. AND second derivatives. So, is there any other way to determine when I can't use the second derivative test?