There are two ways to define the homology groups $H_n(X;R)$:
Via the singular chain complex $C_*(X;R)$ with coefficients in $R$ whose $n$-th component $C_n(X;R)$ is the free $R$-module having as a basis the singular $n$-simplices in $X$. This is completely analogous to the "usual" singular chain complex $C_*(X)$ with coefficients in $\mathbb Z$ . In fact, $C_*(X;\mathbb Z) = C_*(X)$.
For any abelian group $A$ one can define the singular chain complex with coefficients in $A$ by $C_*(X;A) = C_*(X) \otimes_{\mathbb Z} A$.
Clearly, if $A = R$, then 1. and 2. yield naturally isomorphic chain complexes. However, the perspective is somewhat different: In 1. we get a chain complex consisting of free $R$-modules, in 2. we get a chain complex consisting of abelian groups and ignore the $R$-module structure. Therefore in 1. the homology groups $H_n(X;R)$ have the structure of $R$-modules, but in 2. they are only abelian groups. As abelian groups both constructs are identical.
This makes clear that for a path connected space $X$ we have $H_0(X;R) = R$ and $\tilde{H}_0(X;R) = 0$. The proof is exactly the same as for "usual" homology groups.