This is from "Quantum Mechanics in Simple Matrix Form" by Thomas F. Jordan:
$(-i\Sigma_1)(-i\Sigma_2)=-i\Sigma_3$. This corresponds to the fact that the product of rotations by 180 degrees around the 1 and 2 axes is a rotation by 180 degrees around the 3 axis.
Axes 1, 2, and 3 are, of course: x, y, and z, and $\Sigma$'s are the Pauli matrices. But I can't picture why this statement is true. Any help? Is it just true in matrix multiplication?