Why do we need to integrate anything if we already have the rate of growth?
Because there is a Fundamental Theorem of Calculus that says that is how it works.
The number of bacteria is supposed to be some function of time.
Let $F(t)$ be the number of bacteria after $t$ hours. Note that $t$ is a real number within some interval (at least the interval $[0,1]$ since we're given the population at $t=0$ and we're asked about the population at $t=1$).
For example, after one minute the population is $F\left(\frac1{60}\right).$
The plot of the function $F(t)$ is a curved line.
If you had been given a constant rate of growth, like the slope $m$ of a line,
the plot of $F(t)$ would be a straight line and you could compute points along
it using an equation related to lines (as you seem to be trying to do),
$$ y = y_0 + m (x - x_0), $$
but you were given a rate that is different at different values of the time $t$:
the rate at one hour after the start is $4000,$ but the rate half an hour after the start is $1000 \cdot 4^{1/2} = 2000,$ which is quite a bit less;
and the rate fifteen minutes after the start is
$1000 \cdot 4^{1/4} \approx 1414,$ even less still.
So the plot of $F(t)$ is not a straight line and the formula for a straight line is useless.
You don't (initially) know what the function $F(t)$ is, but you do know its derivative:
$$ \frac{\mathrm d}{\mathrm dt} F(t) = 1000 \cdot 4^t. $$
You may also have learned the relevant part or version of the Fundamental Theorem of Calculus (some authors give you a theorem with two parts, some give you a "first theorem" and "second theorem"); possibly you learned the relevant calculation without it being called a theorem. The theorem says that if we have functions $f(t)$ and $F(t)$ with the relationship
$$ f(t) = \frac{\mathrm d}{\mathrm dt} F(t), $$
then
$$ F(b) - F(a) = \int_a^b f(t)\,\mathrm dt. $$
On the left side of this equation you are interested in $F(1)$ and you already have $F(0)$. On the right side you know $f(t)$ for all values of $t,$ and it is a function that is not hard to integrate.