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The comic is here. The equation is: $$ L\left(q\,, \dot{q}\,,t\right) = \mbox{everything}$$

I have tried searching for it, but haven't found it. So I am asking here.

yiyi
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    As Unreasonable Sin has indicated, it indeed refers to the Lagrangian. A related link that this might be referencing is the Standard Model Lagrangian, which can be found here: http://nuclear.ucdavis.edu/~tgutierr/files/stmL1.html – WeierstrassSauce Jul 24 '13 at 05:44

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It's from Lagrangian mechanics. $q$ is a generalized coordinate and $\dot{q}$ is its derivative with respect to time $t$.

http://en.wikipedia.org/wiki/Lagrangian