This is a standard floating-point format called half-precision.
Let's invert the question and ask: How do you represent the number $100.125$ in this format?
The integer part ($100$), has the binary representation $1100100_2$. The fractional part ($.125$) is $\frac{1}{8} = 2^{-3}$, which is simply $.001_2$. Putting it together:
$$100.125_{10} = 1100100.001_2$$
But (most) floating-point numbers need to “normalized”, into scientific notation with exactly one digit to the left of the radix point, so:
$$100.125_{10} = 1.100100001_2 \times 2^6$$
This number conveniently has exactly ten significant bits. So, you might think that we could straightforwardly encode the significand as 1100100001.
But there's a trick here: The first digit of any “normalized” binary number (except zero) is always 1. And the IEEE people decided that it would be a waste of memory to explicitly store a bit that's always 1. So instead, the format is defined to make the leading 1 implied, and use the thus-saved 1 bit of memory to add one bit of precision to the significand.
$$100.125_{10} = (1).1001000010_2 \times 2^6$$
So the significand is thus represented in-memory as the bits 1001000010.
Next, let's deal with the exponent. It's 6, but since the format has an exponent bias of 15, we represent as 6+15 = 21. Or in binary, 10101.
Finally, since the number is positive, the sign bit is 0.
Putting this all together, the half-precision representation of $100.125$ is 0 10101 1001000010. (Or in the more compact hexadecimal representation, 5642.)
OK, so now let's consider the actual bit pattern given:
0 01000 1001000010
- Sign bit
0 = +
- Exponent
01000 = 8. Subtracting the bias of 15 gives an actual exponent of -7.
- Significand
1001000010 = $(1).1001000010_2 = 1 + 2^{-1} + 2^{-4} + 2^{-9} = \frac{801}{512}$. Gee, this looks familiar.
Therefore, the number has a value of $+\frac{801}{512} \times 2^{-7} = \frac{801}{65536} = 0.0122222900390625$.
Note that this value is not equal to $100.125$. It is, in fact, exactly $\frac{1}{2^{13}}$ of $100.125$.
So it seems that your instructor is wrong. They got the significand correct (including the hidden 1 trick), but messed up the exponent somehow.