If $U\subseteq X$ is an open set in a topological space $X$, let $\newcommand{\negation}{\mathop{\sim}}\negation U$ denote the largest open set $V$ such that $V\cap U = \varnothing$ (i.e., the set of points having a neighborhood disjoint from $U$, i.e., the interior of the complement of $U$, i.e., the complement of the closure of $U$).
Note that $U$ is dense iff $\negation U = \varnothing$, or equivalently, $(\negation\negation U) = X$. At the other extreme, open sets such that $(\negation\negation U) = U$ (equivalently, those of the form $\negation V$ for some $V$ open) are known as “regular” open sets.
Clearly, every open set of the form $U \cup \negation U$ is dense. Also, every dense open set is of this form (just take $U$ to be the set itself). But can we do this with $U$ regular? In other words:
Question: Is there an example of a dense open set in $X = \mathbb{R}^n$ that is not of the form $U \cup (\negation U)$ for $U$ regular open? (Equivalently, not of the form $(\negation V) \cup (\negation\negation V)$ for $V$ open.) Or is every dense open set of this form?