I read in a differential geometry textbook that the total signed curvature of a closed plane curve is an integer multiple of $2\pi$. In that same textbook, I also read about Hopf's Umlaufsatz, which states that the total signed curvature of a simple closed plane curve is either $2\pi$ or $-2\pi$. Now, I am interested in a converse of the previous statement. If a closed plane curve has total signed curvature either $2\pi$ or $-2\pi$, must that curve be a simple closed plane curve?
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The "total signed curvature", as you call it, is an isotopy invariant for smooth, oriented, closed plane curves (i.e. immersions of $S^1$ in $\mathbb{R}^2$). The answer to your question is "no" because you can deform a simple closed curve into a nonsimple closed curve. So, for instance, this curve is isotopic to a simple counter-clockwise loop and has the same total signed curvature.
Here's a slightly more interesting-looking example, this time isotopic to a simple clockwise loop.
In general, the total signed curvature is a complete isotopy invariant. If two immersions of $S^1$ have the same total signed curvature, then they are isotopic. That is, one can be deformed to the other through a family of immersions.
Mike F
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Also, if I recall correctly, this is used as a warm-up example in the, by now classic, animation "Outside In" which illustrates the ideas behind Thurston's approach to the 2d sphere eversion problem. I won't put a link here, but it should be easy to google and is strongly recommended viewing for anyone who hasn't seen it. – Mike F Dec 30 '22 at 02:41

