The way those sentences are translated into English depends on the exact meaning of $\Leftrightarrow$: either it's the object-language material implication ($\equiv$ or $\leftrightarrow$) or the meta-theoretic "if...then." I've given translations for each interpretation. I think you're asking about the second, but just to be safe.
$\lnot (\forall x \in U(P(x)) \Leftrightarrow \exists x \in U (\lnot P(x))$
(in the object-language): It's not the case that for all x in U, P holds of x: if and only if for some x in U, P doesn't hold of x.
(in the meta-language): "It's not the case that for all x in U, P holds of x" is true if and only if "for some x in U, P doesn't hold of x" is true.
$\forall x \in U (P(x)) \Leftrightarrow \lnot(\exists x \in U(\lnot P(x))$
(in the object-language): For all x in U, P holds of x: if and only if it's not the case that for some x in U, P doesn't hold of x.
(in the meta-language): "For all x in U, P holds of x" is true if and only if "it's not the case that for some x in U, P doesn't hold of x" is true.
$\lnot(\exists x \in U (P(x)) \Leftrightarrow \forall x \in U (\lnot P(x))$
(in the object-language): It's not the case that for some x in U, P holds of x: if and only if for all x in U, P doesn't hold of x.
(in the meta-language): "It's not the case that for some x in U, P holds of x" is true if and only if "for all x in U, P doesn't hold of x" is true.
$\exists x \in U (P(x) \Leftrightarrow \lnot(\forall x \in U (\lnot P(x)))$
(in the object-language): For some x in U, P holds of x: if and only if it's not the case that for all x in U, P doesn't hold of x.
(in the meta-language): "For some x in U, P holds of x" is true if and only if "it's not the case that for all x in U, P doesn't hold of x" is true.
Generally, first-order formulas are pretty straightforward to translate. Use "it's not the case that" for complex negated sentences, "in" for the membership relation, "holds of" for function or predicate application, and some type of consistent notation for avoiding ambiguities (I like to use colons, but semicolons might also be acceptable).
The first can be written 'not all possible x satisfy P, iff at least one possible x does not satisfy P', with iff meaning 'if and only if'.
– android.weasel Aug 28 '13 at 12:40