The question is a little hard to interpret, I assume that by a set of polynomials generating a subset of $\mathbb C$ you mean that the subset of $\mathbb C$ is the set of common zeros of the polynomials in your set. Of course this means you should only be considering polynomials in a single variable, not in multiple variables as you explicitly stated. So maybe I've misinterpreted you, let me know if I have.
Now assuming I have interpreted your question correctly, what you are asking is whether the Zariski topology on $\mathbb C$ is discrete. The answer is no, the Zariski topology on $\mathbb C$ is the cofinite topology. This means that the closed sets (meaning the sets that arise as the common zeros of a set of polynomials) are exactly the finite subsets of $\mathbb C$ and $\mathbb C$ itself.
To see this first note that $\mathbb C$ is the solution set of the set of polynomials $\{0\}$. For any other set $S$, if $f \in S$ is any nonzero polynomial then $f$ has only finitely many solutions and the common zeros of $S$ must be a subset of this finite set. This shows that every closed proper set is finite. To see that every finite set is closed let $\{a_1, \ldots, a_n\}$ be a finite set of points in $\mathbb C$. Then the zeros of the set $\{f\}$, where $f = (x - a_1)\cdots(x - a_n)$, are exactly the $a_i$.
Edit: For $\mathbb R^2$ the answer is still no, not every subset of $\mathbb R^2$ is the solution set of a set of polynomials. The standard example is the set $\mathbb R^2 \setminus (0, 0)$. I claim that the zero polynomial is the only polynomial that is zero on this set. To see this let $f(x, y) = \sum_{i = 0}^ng_i(x)y^i$ be any polynomial that is zero on $\mathbb R^2 \setminus (0, 0)$. Then for any $a \neq 0$ the polynomial $f(a, y)$ is identically zero. This means each $g_i(x)$ is a polynomial with the property that $g_i(a) = 0$ when $a \neq 0$. As polynomials give continuous functions we then get $g_i(0) = 0$ so $g_i$ is the zero polynomial. Then $f$ is also the zero polynomial.
So we see that no set of polynomials has $\mathbb R^2 \setminus (0, 0)$ as their zeros because those polynomials are zero, and hence give the set $\mathbb R^2$ and not $\mathbb R^2 \setminus (0, 0)$.
More generally, any polynomial that's zero on an open set is zero, so you can't get any subset that contains an open set (open in the Euclidean topology). Also, I don't believe you can get a proper subset of positive Lebesgue measure, but you certainly can't get all subsets of Lebesgue measure $0$ so that's still not a complete characterization.