I'm not sure if you meant to wrote $2^i$ instead of $2^k$, because otherwise you can just take the $2^k$ out of the summation.
For the latter case, we have
$$\sum\limits_{i=0}^{\lfloor\frac{k}{2}\rfloor}2^k\begin{pmatrix}k-i\\i\end{pmatrix} = 2^k\cdot\sum\limits_{i=0}^{\lfloor\frac{k}{2}\rfloor}\begin{pmatrix}k-i\\i\end{pmatrix}$$
Let $a_k$ denote the summation on the right hand side, then we have
\begin{align*}
a_k &= \sum\limits_{i=0}^{\lfloor\frac{k}{2}\rfloor}\begin{pmatrix}k-i\\i\end{pmatrix} = \sum\limits_{i=0}^{\lfloor\frac{k}{2}\rfloor}(\begin{pmatrix}k-i-1\\i-1\end{pmatrix}+\begin{pmatrix}k-i-1\\i\end{pmatrix})\\
&= \sum\limits_{i=0}^{\lfloor\frac{k}{2}\rfloor}\begin{pmatrix}k-i-1\\i-1\end{pmatrix} + \sum\limits_{i=0}^{\lfloor\frac{k}{2}\rfloor}\begin{pmatrix}k-i-1\\i\end{pmatrix}\\
&= \sum\limits_{i=0}^{\lfloor\frac{k}{2}\rfloor-1}\begin{pmatrix}k-2-i\\i\end{pmatrix} + \sum\limits_{i=0}^{\lfloor\frac{k-1}{2}\rfloor}\begin{pmatrix}k-1-i\\i\end{pmatrix}\\
&= a_{k-2}+a_{k-1}
\end{align*}
Also we can compute that $a_0=a_1=1$, so $a_k$ equals the $k$-th Fibonacci number, and the answer is $2^k\cdot F_k$ where $F_k$ denotes the $k$-th Fibonacci number.
If it's the former case, call the whole summation $b_k$, then you should arrive a recursion $b_k = b_{k-1} + 2b_{k-2}$ by similar means. The sequence is given by https://oeis.org/A001045.
By the way, you might want to pay more attention to your tags, since I can't think of any possible way of this problem relating to linear algebra.