Since the instructions are not to use any R or M, the first thing I'd do is omit them from the stock of available letters:
REMEMBRANCE --> EEBANCE
Now the problem can be done (tediously) by writing out all possibilities. To simplify matters, let's apply the final constraint of using at least two E's. Since there are only three E's available, that means two cases: we use exactly two E's or we use exactly three E's.
The case where three E's are used (to create a "word" of four letters) is especially easy to number. Where does the non-E character go in the word (permutations with repetitions), or if you don't consider order important (combinations with repetitions), simply how may ways are there to choose a letter that is not E?
The case where two E's are used should be tractable after you've done the warm-up exercise with three E's.