Remainder is what is left when you make integer division. In equations: Say you want to divide $p$ by $q$. You can always find an integer $m$ and an integer $0\le r<q$ such that
$$p=m\cdot q+r$$
or equivalently
$$r=p-m\cdot q$$
$r$ here is your remainder. For instance if you want to divide $p=25$ by $q=3$, you can realize that it the answer is a bit more than $8$ but less than $9$ since $3\cdot8=24<25$ and $3\cdot9=27>25$. With this you can choose $m=8$ and write $25 = 8\cdot 9 + 1$. This means that the remainder of $25$ when divided by $3$ is $1$.
Because of the restriction $0\le r<q$, then when you divide by $q=3$ the possible remainders are: $0,1,2$. If $p$ is a multiple of $3$, by definition, then the remainder must be $0$. Hence only remainders $1$ and $2$ are possible if $p$ is not a multiple of $3$, or in other words, if $3$ does not divide $p$