$$\iint_{R}^{} x \sin(6x + 7y) - 3y \sin(6x + 7y) dA$$
So I chose $u = 3y$ and $v = 6x + 7y$. So then $x$ will be replaced with $\frac{3u - 7v}{18}$. It seems correct, but does this truly "simplify" the integrand? Or have I done something incorrectly?