No, this is not true. Weak convergence is sensitive to the space of test functions we use.
Let $d$ be the dimension of our space. Consider the sequence
$$u_n = n^r \chi_{\{|x|\le 1/n\}} $$
where $r\in (0,d)$ is to be determined. The $L^p$ norm of $u_n$ is a constant multiple of $n^{r- d/p}$. Therefore, for $p<d/r$ we have $u_n\to 0$ strongly in $L^p$, whereas for $p>d/r$ the sequence is unbounded, and therefore does not converge even weakly in $L^p$.
Let's rephrase this in terms of dual spaces, using the Hölder conjugate exponent $(d/r)'=\frac{d}{d-r}$.
- If $v\in L^q$ with $q>\frac{d}{d-r}$, we have $\int u_n v \to 0$. (Hölder's inequality)
- There exists $v\in L^q$ with $q<\frac{d}{d-r}$ such that $\int u_n v \not\to 0$. (Weak convergence fails)
That's pretty sensitive.
Assume $0\in\Omega$. By the Sobolev embedding theorem, every function in $H^1(\Omega)$ belongs to $L^{2^*}(B)$ where $2^*=\frac{2d}{d-2}>2$ and $B$ is some ball around $0$. Choose $r$ so that $\frac{d}{d-r}$ is strictly between $2$ and $2^*$, and you have a counterexample.