You can do integration by parts like this, without substituting. Of course, substituting is fine and all, but you'll have to use Integration by Parts three times either way.
$$\begin{align}
\int_0^1xe^{\sqrt{x}}\,dx
&=\int_0^1\frac{2x\sqrt{x}}{2\sqrt{x}}e^{\sqrt{x}}\,dx\\
&=\int_0^12x\sqrt{x}\left(\frac{1}{2\sqrt{x}}e^{\sqrt{x}}\,dx\right)\\
&=\left[2x\sqrt{x}e^{\sqrt{x}}\right]_0^1-\int_0^13\sqrt{x}\,e^{\sqrt{x}}\,dx\\
&=\left[2x\sqrt{x}e^{\sqrt{x}}\right]_0^1-\int_0^13\sqrt{x}\,e^{\sqrt{x}}\,dx
\end{align}$$
And we've reduced the intebrand from $cx^1e^{\sqrt{x}}$ to $cx^{1/2}e^{\sqrt{x}}$. Repeat the technique two more times to bring it to $cx^{-1/2}e^{\sqrt{x}}$, and then you can just directly antidifferentiate.