Let $m\leq n$ be nonnegative integers and $x > 0$. I would like to find sufficient conditions on $m,n,x$ (as tight as possible) s.t.
$$\frac{ \binom{n}{m} \sum_{j=0}^m j\binom{n}{m-j}x^j }{ x \left( \sum_{j=0}^m \binom{n}{m-j} x^j \right)^2 } < 1$$
Let $m\leq n$ be nonnegative integers and $x > 0$. I would like to find sufficient conditions on $m,n,x$ (as tight as possible) s.t.
$$\frac{ \binom{n}{m} \sum_{j=0}^m j\binom{n}{m-j}x^j }{ x \left( \sum_{j=0}^m \binom{n}{m-j} x^j \right)^2 } < 1$$
So we have
$$ \binom{n}{m} \sum_{j=0}^m j\binom{n}{m-j}x^j < x \left( \sum_{j=0}^m \binom{n}{m-j} x^j \right)^2 $$
or
$$ \binom{n}{m} \sum_{j=0}^m j\binom{n}{m-j}x^j < x \left( \sum_{j=0}^m\sum_{k=0}^m \binom{n}{m-j} \binom{n}{m-k} x^j x^k\right) $$
or
$$ \binom{n}{m} \sum_{j=0}^m j\binom{n}{m-j}x^j < x\left( \sum_{j=0}^m\sum_{k=0}^m \binom{n}{m-j} \binom{n}{m-k} x^{j+k}\right) $$
On the right let $j=s+t$ and $k=t-s$ so $2t=j+k$ and $2s=j-k$.
$$ \binom{n}{m} \sum_{j=0}^m j\binom{n}{m-j}x^j < x\left( \sum_{t=0}^m\sum_{s=-m}^m \binom{n}{m-s-t} \binom{n}{m-t+s} x^{t}\right) $$
Moving the $x$ into the summation and noting that for $j=0$ the summation on the right vanishes,
$$ \binom{n}{m} \sum_{j=1}^m j\binom{n}{m-j}x^j < \left( \sum_{t=0}^m\sum_{s=-t}^t \binom{n}{m-s-t} \binom{n}{m-t+s} x^{t+1}\right) $$
Making the substitution $j=j-1$,
$$ \binom{n}{m} \sum_{j=0}^{m-1}(j+1)\binom{n}{m-j}x^{j+1} < \sum_{t=0}^m x^{t+1}\left( \sum_{s=-t}^t \binom{n}{m-s-t} \binom{n}{m-t+s}\right) $$
Linear independence of $x^j$ tells us that we require the following for all $j=0,...,m-1$
$$ \binom{n}{m}(j+1)\binom{n}{m-j} < \left( \sum_{s=-j}^j \binom{n}{m-s-j} \binom{n}{m-j+s}\right) $$
Rewriting this,
$$ \frac{n!}{m!(n-m)!}(j+1) \frac{n!}{(m-j)!(n-m+j)!} < \sum_{s=-j}^j \frac{n!}{(m-s-j)!(n-m+s+j)!}\frac{n!}{(m+s-j)!(n-m-s+j)!}$$
And this is exact. You can try to put this in MATLAB or excel to play around with various m and n.
One more simplification can be performed $$ \frac{(j+1)}{m!(n-m)!(m-j)!(n-m+j)!} < \sum_{s=-j}^j \frac{1}{(m-s-j)!(n-m+s+j)!(m+s-j)!(n-m-s+j)!}$$
Note: This is only a rudimentary answer to your question together with some additional information at the end.
A short overview:
First step Transformation of the inequality
The idea is to transform the inequality so that we can better see, which parts are responsible to invalidate it.
\begin{align*} 0<x\left(\sum_{j=0}^{m}\binom{n}{m-j}x^{j}\right)^2-\binom{n}{m}\sum_{j=0}^{m}\binom{n}{m-j}jx^j\tag{1} \end{align*}
Regrettably we hardly have a chance to find a closed formula for \begin{align*} \sum_{j=0}^{m}\binom{n}{j}x^j \qquad 0\leq m\leq n\tag{2} \end{align*} since as you can read e.g. in the second edition of
Concrete Mathematics from Graham, Knuth and Patashnik
There is no closed form for the partial sum of a row of Pascal's triangle.
But we find another interesting hint in section 5.1 for a closed formula in case (2) is multiplied by it's distance to the center:
\begin{align*} \sum_{j=0}^{m}\binom{n}{j}\left(\frac{n}{2}-j\right)=\frac{m+1}{2}\binom{n}{m+1} \tag{3} \end{align*}
We use a similar technique to transform the inequality and so unify the sums from (1).
Let \begin{align*} A_{m,n}(x)&=\sum_{j=0}^{m-1}\binom{n-1}{j}x^{m-j}\qquad 1\leq m\leq n \end{align*} then \begin{align*} \sum_{j=0}^{m}\binom{n}{m-j}x^{j}&=\binom{n-1}{m}+(1+x)A_{m,n}(x)\\ \sum_{j=0}^{m}\binom{n}{m-j}jx^{j}&=m\binom{n-1}{m}+\left(m-(n-m)\frac{1}{x}\right)A_{m,n}(x)\\ \end{align*}
Note: We use the convention, that the empty sum and binomial coefficient $\binom{n}{j}$ with $n<0$ is considered to be $0$.
The statement above is valid since \begin{align*} \sum_{j=0}^{m}&\binom{n}{m-j}x^{j}=\sum_{j=0}^{m}\binom{n}{j}x^{m-j}\\ &=\sum_{j=0}^{m}\binom{n-1}{j}x^{m-j}+\sum_{j=1}^{m}\binom{n-1}{j-1}x^{m-j}\\ &=\sum_{j=0}^{m}\binom{n-1}{j}x^{m-j}+\frac{1}{x}\sum_{j=0}^{m-1}\binom{n-1}{j}x^{m-j}\\ &=\binom{n-1}{m}+(1+x)A_{m,n}(x)\\ \end{align*}
and \begin{align*} \sum_{j=0}^{m}&\binom{n}{m-j}jx^{j}=\sum_{j=0}^{m}\binom{n}{j}(m-j)x^{m-j}\\ &=m\sum_{j=0}^{m}\binom{n}{j}x^{m-j}-\sum_{j=1}^{m}\binom{n}{j}jx^{m-j}\\ &=m\sum_{j=0}^{m}\binom{n}{j}x^{m-j}-n\sum_{j=1}^{m}\binom{n-1}{j-1}x^{m-j}\\ &=m\left(\sum_{j=0}^{m}\binom{n-1}{j}x^{m-j}+\sum_{j=1}^{m}\binom{n-1}{j-1}x^{m-j}\right)\\ &\qquad-\frac{n}{x}\sum_{j=0}^{m-1}\binom{n-1}{j}x^{m-j}\\ &=m\left(\sum_{j=0}^{m}\binom{n-1}{j}x^{m-j}+\frac{1}{x}\sum_{j=0}^{m}\binom{n-1}{j}x^{m-j}\right)\\ &\qquad-\frac{n}{x}\sum_{j=0}^{m-1}\binom{n-1}{j}x^{m-j}\\ &=m\binom{n-1}{m}+\left(m-(n-m)\frac{1}{x}\right)A_{m,n}(x)\\ \end{align*}
Now putting all together gives
\begin{align*} 0<&x\left(\sum_{j=0}^{m}\binom{n}{m-j}x^{j}\right)^2-\binom{n}{m}\sum_{j=0}^{m}\binom{n}{m-j}jx^j\\ &=x\left(\binom{n-1}{m}+\left(1+\frac{1}{x}\right)A_{m,n}(x)\right)^2\\ &\qquad-\binom{n}{m}\left(m\binom{n-1}{m}+\left(m-(n-m)\frac{1}{x}\right)A_{m,n}(x)\right)\\ \end{align*}
And after some rearrangement we finally get the
Resulting inequality: \begin{align*} A_{m,n}&=\sum_{j=0}^{m-1}\binom{n}{m-j}x^{m-j}\qquad 1\leq m \leq n,\quad x> 0\\ \\ 0<&(1+x)^2A_{m,n}^2(x)\\ &+\binom{n-1}{m}\left(2x^2+\left(2-\frac{nm}{n-m}\right)x+n\right)A_{m,n}(x)\\ &+\binom{n-1}{m}^2x\left(x-\frac{nm}{n-m}\right)\\ \end{align*}
Observe, that the only factors which could become negative in the equality above are \begin{align*} 2x^2+\left(2-\frac{nm}{n-m}\right)x+n\qquad\text{and}\qquad x-\frac{nm}{n-m}\tag{4} \end{align*} We see, that in case of fixed $x$ and growing $n$ the terms become more and more negative as $m$ is approaching $n$. But we also know that $A_{m,n}^2$ grows very fast, when $m$ approaches $n$. This is immediately clear if we consider $$\sum_{j=0}^{n}\binom{n}{j}=2^n\qquad\text{and}\qquad\sum_{j=0}^{m}\binom{2m+1}{j}=\frac{1}{2}2^{2m+1}$$
So, a further elaboration could have a look at the zeroes of (4) and try to analyse the resulting regions with negative values together with the growing behaviour of $A_{m,n}$.
Step 2: Some special values
Which I did only for curiosity to get a first impression of the inequality. In the following we always assume $x>0$.
m=0 valid for $n\geq0$
You can see immediately that the inequality (1) is valid for all $x>0$ and $n\geq0$.
m=1 valid for $n>0$
This leads to the inequality $(n+x)^2-n>0$ which is also valid for all $n>0$.
m=2 valid for $n>4$
With the help of Wolfram Alpha we find $n\geq 4.69858$ and $x>0$.
The corresponding inequality is
$$x^4+2nx^3+n(2n-1)x^2+n^2(n-1)x+\frac{1}{4}n^2(n-1)^2>0$$
m=n valid for $n>0$.
with inequality
$$(x+1)^{n+1}-n>0$$
m=n-1 valid for $n>0$.
with inequality
$$\frac{1}{x}\left((x+1)^{n}-1\right)^2-\frac{n}{x}\left((x+1)^{n-1}\left(nx+(x+1)\right)+1\right)>0$$
Step 3: Some additional info
Here is some related information which may be helpful when estimating the sum $\sum_{j=0}^{m}\binom{n}{m}$ for large values of $n$.
For what it's worth, Mathematica gives a closed form in terms of the hypergeometric functions, which may or may not be helpful if you are proficient with them:
$$ \sum_{j=0}^m j \binom{n}{m-j} x^j = x \binom{n}{m-1} {}_2F_1(2, 1-m; -m+n+2; -x) $$
$$ \sum_{j=0}^m x^j \binom{n}{m-j} = \binom{n}{m} {}_2F_1 (1, -m; -m+n+1; -x) $$
http://www.wolframalpha.com/input/?i=sum+j+binomial%28n%2C+m-j%29+x%5Ej+for+j%3D0..m
http://www.wolframalpha.com/input/?i=sum+binomial%28n%2C+m-j%29+x%5Ej+for+j%3D0..m