You have an ordinary linear differential equation, so you can use linear algebra to help understand. If you can solve
$$ 5 f'' + 3 f' = x^k $$
for all $k$, then you can take the appropriate linear combinations to obtain solutions to your equation of interest.
If you want to be really sneaky, you can select a different basis for $P(\mathbb{R})$ that makes the equation really easy to solve, such as
$$ 5f'' + 3f' = 5(k+2)(k+1) x^{k} + 3(k+2) x^{k+1} $$
(which has solution $f = x^{k+2}$), along with a solution to
$$ 5f'' + 3f' = 1$$
which is also easy to solve.
It may be better to think of this as turning the question around: rather than asking whether, for any polynomial $p$, you can find a polynomial $q$ such that $5q'' + 3q' = p$, you should instead ask the questions "which polynomials $p$ can be the value of $5q'' + 3q'$?" That is, find the image of the linear transformation $q \mapsto 5q'' + 3q'$.